1.d4 Nf6 2.c4 e6 3.Nf3 b6 4.g3 Bb7 5.Bg2 Be7 6.Nc3 Ne4 7.Bd2 f5 It's very hard to specifically prepare for Morozevich as he is playing many different openings. One has to be ready even for the Albin Countergambit. Nevertheless, Gelfand probably analysed this position with his seconds. The classical Queens Indian defence with delayed castle, where white can try d5.
8.d5 Bf6 9.Qc2 Qe7 10.Nxe4 fxe4 11.Qxe4 Bxb2 12.Rd1 Bf6 13.O-O Na6 14.Nd4 Nc5 15.Qe3 This move is a novelty, GM Burmakin played Qg4 in one of his games.
15... exd5 16.cxd5 Qxe3 17.Bxe3 O-O-O 18.Rb1 Rhe8 19.Nb5 Rxe3!? Interesting exchange sacrifice. Black will play on the activity of his pieces and better pawn structure. 19...a6 would have allowed 20. Bxc5 bxc5 and black king might be in trouble later.
20.fxe3 a6 21.Nd4 Re8 22.Nf5 d6 22...Na4 was interesting, but I guess Morozevich wanted to prevent any kind of d6 push for white.
23.Rb4 h5 24.g4 a5 25.Rbf4 Rh8 26.gxh5 Rxh5 27.Rg4 Rh7 28.Nxg7 Rxg7 29.Bh3 Rxg4+ 30.Bxg4+ Kd8 31.Rxf6 Bxd5 32.a3 b5 33.h4 b4 34.axb4 axb4 35.Rf4 b3 36.Bf5 Bf7 Necessary to prevent Bg6 and h5.
37.Kf2 Ke7 38.Ke1 Kf6 39.Bd3+ Kg7 40.Kd2 Be6 41.Kc3 Time control has passed and Morozevich has to figure how to stop white's perspective plans. Gelfand might try to exchange the bishops with Bc4 or go after c7 pawn with his rook. The biggest problem, of course, is passed h-pawn.
41... Bf7 42.Bc4 Bxc4 43.Rxc4 Kg6 44.e4 Ne6 45.Kxb3 Kh5 46.e5 d5 47.Rb4 Kg6 48.Rb8 Nd4+ 49.Kb2 Nf5 50.Rf8 1-0